Try This Challenging Board Review Question About Hematologic Disorders

Welcome to the next episode of The Reveal where we take you inside the mind of a test-taker to deconstruct and connect the dots of a board-style question so you can become a better student, transform how you learn, and excel not only on high-stakes exams, but also in your general medical knowledge. Let’s get started.

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A 57-year-old man presents to the ED with severe dyspnea and frothy sputum. His wife notes he has a “blood problem” that his doctor is monitoring. On physical exam, you note bilateral pulmonary rales to the mid-thorax. Vital signs are BP 124/78 mm Hg, HR 140 beats per minute, RR 35 breaths per minute, and T 99.5°F. Which of the following is the most common etiology of this disease process?

A) Acute myeloid leukemia

B) Multiple myeloma

C) Polycythemia vera

D) Waldenstrom macroglobulinemia

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